the infusion of calumbo and effervescing draughts, (composed of citric acid and bicarbonate of potash), in those occasional attacks of vomiting especially observed in delicate females, and which are commonly termed bilious attacks." Authors might be multiplied to a great amount, who speak highly of the employment of columbo in vomiting occasioned from a variety of causes. There remains not a doubt, that in many cases it evinces a positive power of arresting vomiting.

DYSENTERY.-When tonics are indicated in the latter periods of dysentery, and the inflammatory symptoms have subsided, columbo often proves serviceable, It may, even, be administered when many other tonics could not be tolerated by the patient. Dr. King alludes to its use in this disease, and as an agent of no ordinary repute. Waring speaks of its efficacy in many affections, as effectually allaying the irritability, and improving the digestive organs, promoting the appetite, and imparting tone to the system generally. Dr. Percival states, as mentioned by Stillé, of his own knowledge that it is serviceable in moderating the violence of the early symptoms of dysentery, but still more so as a cordial and tonic towards the decline of the attack. Dr. Copland makes favorable mention of columbo, as a tonic, in certain forms and stages of this malady. It will be found beneficial, often, to administer this agent in conjunction with small doses of opium and camphor, or cases may occur in which ipecacuanha, or the infusion of serpentaria will be found valuable adjuvants, in conjunction with, or, alternated with columbo. This disease prevailed in Flanders some years since, and in various parts of the north of France. In some villages nearly all the inhabitants were said to have been attacked the same day. Various remedies are mentioned, as having been used, but columbo appears to have been the principle tonic administered. When astringents are being used, this agent may, with safety, be entered upon. Frasera caroliniensis, the American columbo, is considered, by some writers, equal if not superior to the foreign columbo, as a tonic. Dr. H. G. Lungreen, Franklin, N. C., says that he has used the American columbo, and it has proved valuable in his hands, in the treatment of dysentery, cholera morbus, cholera infantum, and bilious cholic, affections for which the foreign columbo has been used. Dr. Hildreth, of Ohio, states "that from the experiments he has made with it, (American co

lumbo) he is induced to believe it fully equal, if not superior to the imported, and mentions a case of gangrene of the lower extremities, in which it had proved successful, after bark and other remedies had failed."

INTERMITTENT FEVER.-Dr. King observes, in relation to the use of the cocculus palmatus;-"Like other strong bitters, it occasionlly checks the remittent and intermittent fevers of hot climates." A powerful tonic, he says, may be formed of the alcoholic extract of the root. Many patients can not tolerate the quinine treatment in doses sufficiently large to arrest the disease.

In such cases, full doses of the extract of columbo should be administered every four hours, alternated with small doses of quinine, so as not to disturb the patient with any indications of cinchonism. As has been remarked, columbo may be advantageously combined with other tonics, or with sedatives.

COMPOUND INFUSION OF COLUMBO.

Fluid Extract of Columbo,

Water,

1 ounce.

DOSE-Two drams every hour in atony of the intestines, manifest

DOSE-Two ounces every two hours in chronic diarrhoea.

3. Fluid Extract of Columbo,

1 dram

Water,

DOSE-One dram in diarrhoea.

MIXTURE OF COLUMBO AND CASCARILLA.

DOSE-One dram every hour, in chronic diarrhoea.

COMPOUND PILLS OF COLUMBO.

Solid Extract of Columbo,

Oil of Caraway,

Syrup of Saffron,

Rhubarb,
Chamomile,

Make into four grain pills.

DOSE-Four a day in mania, with amenorrhoea.

1 ounce.

6

66

BERENDS.

1 dram

2 scruples. 2 drams.

5 drops. sufficient

PRACTICAL NOTES.

BY THEODORE C. MILLER, M. D.

VERATRUM VIRIDE IN CONSTIPATION.-In an obstinate case of habitual obstruction of the intestines, I gave three drops, five times

daily, of the Tincture of Veratrum Viride, and in the course of two weeks, effected an entire recovery.

CONSTIPATION.-In another obstinate case I found the following an effectual eccoprotic.

B. Podophylli,

Cinchona Sulp.

gr. iv.

gr. x.

M. f. pil. n. xx S. One pill every night at bed time.

DIABETES.—A patient of mine, suffering from diabetes, received great benefit from a combination of:

Phosphoric Acid,

Fluid Extract of Calisaya Bark,

Fluid Extract of Bugle Weed.

Prior to the employment of this mixture several agents had been resorted to without any curative or palliative effect.

CHRONIC DIARRHEA.—The following prescription in my practice, is a favorite with me, to combat chronic diarrhea :

Misce. D. S. One powder in the morning, middle of the day, and at night.

In the diarrhea depending upon atony of the intestines, I use fluid extract of columbo. In some cases I add fluid extract of cascarilla and rhei.

DYSENTERY. In several cases of dysentery I have used with excellent effect, aqua calcis with tinct. of opium, conjoining the same with a topical application of spirits of camphor to the abdomen. In the advanced stage, when there is no fever I frequently advise the following prescription:

B. Fluid Extract of Gentian,

Fluid Extract Rhei.

Fluid Extract Cinnamon,

3 iss.

- 3 ss.

Fluid Extract of Leptan,

M. S. Every hour a teaspoonful.

In case the patient is low and nervous, use:

B.

Spirits of Camphor,

Deodorized Tinct. of Opium,

Tincture of Crocus,

M. S. Twenty drops four times daily. To combat the fever there is no better medicine than the tincture of aconite in small. doses.

ANALYSES OF HOT SPRINGS, ARKANSAS.

BY P. H. ELLSWORTH, M. D.

I propose to give the different analyses made under the guidance of Dr. David Dale Owen, State Geologist. He says: "In June, 1858, I made a partial examination of the waters of the Hot Springs, by boiling down one and a half gallons of the waters taken from the Kitchen Spring, and found the contents approximately reduced to one gallon, as follows:

Grammes.

Organic Matter, combined with some moisture, 1·16
Silica, with some Sulphate of Lime not dis-

During the winter of 1859, Dr. William Elderhorst (then Chemical Assistant to the Survey) analyzed 1000 grammes of the socalled Arsenic Spring, and found it to contain :