Leading Pharmaceutical Innovation: Trends and Drivers for Growth in the Pharmaceutical IndustrySpringer Science & Business Media, 19 de fev. de 2008 - 186 páginas Pharmaceutical giants have been doubling their investments in drug development, only to see new drug approvals to remain constant for the past decade. This book investigates and highlights a set of proactive strategies, aimed at generating sustainable competitive advantage for its protagonists based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of internationalisation, such as outside-in innovation in the early phases of R&D. Our findings are illustrated not only in cases of Swiss pharmaceutical industry, but also by industry cases from the US and Asia. |
Conteúdo
| 1 | |
Do You Really Want to Be in This | 19 |
How to Find | 33 |
How to Organize | 50 |
The Importance of Project and Portfolio Management | 65 |
Impact of Outsourcing on Pharmaceutical RD | 71 |
Accessing Earlystage Innovation | 78 |
Commercializing Internal Research Results | 86 |
How to Commercialize a Breakthrough Technology | 95 |
Where to Get Access | 103 |
Management Answers to Pharmaceutical RD Challenges | 123 |
Future Directions and Trends 159 | 158 |
| 165 | |
Glossary | 179 |
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Aliskiren approval AstraZeneca Aventis Bayer billion biotech biotechnology biotechnology companies blockbuster drugs blockbuster sales centers ceutical chemical China clinical development clinical trials co-development combinatorial chemistry commercialization company’s complex compound costs disease drug candidate drug development drug discovery drug’s external partners Gassmann Genentech genes genetic genomics GlaxoSmithKline global growth healthcare high-throughput screening improve in-licensing increased InnoGel Intarcia intellectual property international R&D investment know-how launch Lipitor maceutical manufacturing medicines ment molecular molecule Novartis out-licensing outsourcing overall patent protection percent Pfizer phar pharma pharmaceutical companies pharmaceutical industry pharmaceutical innovation pharmaceutical products pharmaceutical R&D pharmaceutical research pharmacogenomics pipeline portfolio potential pre-clinical Project Management proteins proteomics R&D activities R&D collaborations R&D internationalization R&D management R&D process R&D projects Reepmeyer research and development Reuters revenues risks Roche soft capsule Speedel stages strategy structure substance success Swiss Switzerland target technical evaluation technologies therapy areas tion value chain worldwide
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