Clinical Trials: A Practical Guide to Design, Analysis, and ReportingRemedica, 2006 - 480 páginas The author takes a back-to-basics approach to explaining statistics specifically for a medically literate audience. Each article provides essential background information to each topic, explores its meaning, and explains how and when it should be applied. Medical students, statistics students, clinical researchers, pharmaceutical sales representatives Statistics are complicated, but to a large extent this is a reflection of the way in which they are taught. In this book, Dr Bahkar takes a back-to-basics approach to explaining statistics specifically for a medically literate audience. Based on the successful "Practical Issues in Clinical Trial Design" series published in Remedica's flagship journal Clinical Researcher, and supplemented by key contributions from other leading international experts, each article provides essential background information to each topic, explores its meaning, and explains how and when it should be applied. Readers will gain not only an understanding of the basics of medical statistics, but also critical insight into how to review and evaluate clinical trial evidence. |
Conteúdo
Introduction | |
IntentiontoTreat Analysis 255 | |
Subgroup Analysis 265 | |
Randomized Clinical Trials 1 | |
Patient Selection 47 | |
Randomization 65 | |
Crossover Trials 91 | |
Equivalence Trials 113 | |
Repeated Measurements 317 | |
Multiplicity 329 | |
Missing Data 339 | |
Interim Monitoring and Stopping Rules 353 | |
Reporting of Trials | |
Overview of Reporting 365 | |
Trial Profile 377 | |
Presenting Baseline Data 385 | |
Cluster Randomized Trials 141 | |
Types of Data and Normal Distribution 167 | |
Significance Tests and Confidence Intervals 185 | |
Comparison of Means 197 | |
Analysis of Survival Data 235 | |
Regression Analysis 273 | |
Adjustment for Covariates 287 | |
Confounding 295 | |
Use of Tables 391 | |
Use of Figures 407 | |
Critical Appraisal of a Report 427 | |
MetaAnalysis 439 | |
Glossary 453 | |
Abbreviations 461 | |
Index 467 | |
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Clinical Trials: A Practical Guide to Design, Analysis, and Reporting Ameet Bakhai,Duolao Wang Prévia não disponível - 2006 |
Termos e frases comuns
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